Animal and plant species exhibit an astonishing diversity of sexual systems, including environmental and genetic determinants of sex, with the latter including genetic material in the mitochondrial genome. In several hermaphroditic plants for example, sex is determined by an interaction between mitochondrial cytoplasmic male sterility (CMS) genes and nuclear restorer genes. Specifically, CMS involves aberrant mitochondrial genes that prevent pollen development and specific nuclear genes that restore it, leading to a mixture of female (male‐sterile) and hermaphroditic individuals in the population (...) (gynodioecy). Such a mitochondrial‐nuclear sex determination system is thought to be rare outside plants. Here, we present one possible case of CMS in animals. We hypothesize that the only exception to the strict maternal mtDNA inheritance in animals, the doubly uniparental inheritance (DUI) system in bivalves, might have originated as a mitochondrial‐nuclear sex‐determination system. We document and explore similarities that exist between DUI and CMS, and we propose various ways to test our hypothesis. (shrink)

Abstract Employing an extended case method ethnography (Burawoy 1998), the researcher joined five new members forming a spiritualist's group under the leadership of an experienced advocate. Over a period of eighteen months, the researcher attended all the group's activities and events. Data were collected to reflexively interrogate the process theory of conversion proposed by Lewis Rambo (1993). The data revealed conversion to be a multifaceted and dynamic process of cognitive change, mediated by structural, and contextual forces. The results provide a (...) reconceptualization of Rambo's theory, presenting a theoretical expansion of the model emphasizing its mechanisms of action. The paper details the composition of the “Interaction-Commitment” mechanism, operationalized within four submechanisms emanating from Rambo's roles, rituals, rhetoric, and relationships. This longitudinal study shows that most of the hard work toward conversion occurs before any formal interaction with a conversion advocate. Conversion operates most effectively under conditions of cognitive economy wherein the belief path follows a path of least cognitive expenditure. (shrink)

There is a bias in neuroscience toward localizing and modularizing brain functions. Single cell recording, imaging studies, and the study of neurological deficits all feed into the Gallian view that different brain areas do different things and the things being done are confined to particular processing streams. At the same time, there is a growing sentiment that brains probably don’t work like that after all; it is better to conceive of them as fundamentally distributed units, multi‐tasking at every level. This (...) sentiment, however, is much less congenial to the tried‐and‐true experimental protocols available today and to theorizing about the brain in general. This essay examines the tension between current experimental methods and large-scale views of the brain. We argue that this disconnection between experiment and what really are guiding theoretical metaphors seriously impedes progress in neuroscience. (shrink)

There is a bias in neuroscience toward localizing and modularizing brain functions. Single cell recording, imaging studies, and the study of neurological deficits all feed into the Gallian view that different brain areas do different things and the things being done are confined to particular processing streams. At the same time, there is a growing sentiment that brains probably don’t work like that after all; it is better to conceive of them as fundamentally distributed units, multi‐tasking at every level. This (...) sentiment, however, is much less congenial to the tried‐and‐true experimental protocols available today and to theorizing about the brain in general. This essay examines the tension between current experimental methods and large-scale views of the brain. We argue that this disconnection between experiment and what really are guiding theoretical metaphors seriously impedes progress in neuroscience. (shrink)

Presents a plethora of approaches to developing human potential in areas not conventionally addressed. Organized in two parts, this international collection of essays provides viable educational alternatives to those currently holding sway in an era of high-stakes accountability.

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 697 however, that extreme caution is to be advised upon entering those waters? Fully respectful of this concern, Professor Stambaugh enjoins the reader to "reach his own conclusions about parallels and affinities" concerning "some strains of Nietzsche's thought that are most consonant with an Eastern temper of experience." DAVID B. ALLISON SUNY, Stony Brook W. J. Mander. An Introduction to Bradley's Metaphysics. New York: Oxford University Press, (...) 1994. Pp. viii + 175. Cloth, $39-95. T. L. S. Sprigge. James and Bradley: American Truth and British Reality. Chicago: Open Court, 1993. Pp. xiv + 63o. Cloth, $66.95. Paper, $29.95Until the appearance of Mander's book there had been no short general introduction to Bradley in print since Penguin dropped Wollheim's F. H. Bradley from their list. But in any case, as a result of the work of scholars since its last revision in 1969, Wollheim's account, despite its many virtues, is now known to be misleading in crucial places, for he remained to some extent in the grip of the dismissive caricature of Bradley bequeathed to analytic philosophers by Russell and Moore and stilloften just taken for granted. (See, e.g., almost any textbook which has a chapter on truth.) By drawing on this scholarship Mander offers us a philosopher strikingly different from this caricature. Mander's replacement portrayal is, in its broad outlines, accurate enough to be confidently recommended as giving a good general sketch of Bradley's views (excepting the ethics, which Woliheim managed to include), presenting them sympathetically but not completely uncritically in a way which should offer something of interest to both advanced undergraduates and their teachers. As Oxford has also recently published a selection from Bradley's works (Writings on Logic and Metaphysics, edited by James Allard and Guy Stock, with both general and topic-specific introductions), there is the added benefit that one who wishes to read him can now do so without being faced with wading through some intimidatingly large volumes of often meandering discussion in baffling prose. The two should make a good pair around which to structure classes concerning Bradley. I am not quite so confident about some of the detail of Mander's account, which is, moreover, sometimes explained in a way nearly as obscure as the original on which it is intended to cast light. This last is, of course, hard to avoid in expounding a writer whose whole cast of mind is opposed to the exact formulation of precise theses illustrated with clear examples, and is less misleading than artificial precisification; it also perhaps reduces the risk that students will use it as a substitute for, rather than a guide to, the primary texts themselves. And I want to stress that Mander's overall picture of Bradley's views seems to me reliable and as well situated historically as the book's ' G. M. C. Sprung, "Nietzsche's Interest in and Knowledge of Indian Thought," in The Great Yearof Zarathuara (188z-1981), ed. David Goicoechea (Lanham, MD.: University Press of America, x983), 166-8o. 698 JOURNAL OF THE HISTORY OF PHILOSOPHY 33:4 OCTOBER 1995 brevity allows. Its usefulness is enhanced by a very full bibliography which does include some coverage of the ethics. Sprigge's massive work is far more ambitious. His aim is "to provide a comparative exposition and personal evaluation of [Bradley's and James's] main views on truth and on the general nature of reality" (xiii). He gives several reasons for selecting these two philosophers for attention: they are the most important of their time; they are misunderstood and misrepresented; and their views have much in common that is largely correct while being the main alternative solutions to the problems they confront. Further, ajoint treatment makes sense because "it is toJames, rather than Russell, let alone Moore, that we must look for a serious critique of Bradley" (417). This is a labor of love, exhibiting reading of remarkable breadth and depth and the familiarity with its subject matter that is the product only of decades of exploration. Perhaps this very familiarity is part of the explanation of an occasional paucity of textual backup for the pictures Sprigge... (shrink)

Should laws about sex and pornography be based on social conventions about what is disgusting? Should felons be required to display bumper stickers or wear T-shirts that announce their crimes? This powerful and elegantly written book, by one of America's most influential philosophers, presents a critique of the role that shame and disgust play in our individual and social lives and, in particular, in the law.Martha Nussbaum argues that we should be wary of these emotions because they are associated in (...) troubling ways with a desire to hide from our humanity, embodying an unrealistic and sometimes pathological wish to be invulnerable. Nussbaum argues that the thought-content of disgust embodies "magical ideas of contamination, and impossible aspirations to purity that are just not in line with human life as we know it." She argues that disgust should never be the basis for criminalizing an act, or play either the aggravating or the mitigating role in criminal law it currently does. She writes that we should be similarly suspicious of what she calls "primitive shame," a shame "at the very fact of human imperfection," and she is harshly critical of the role that such shame plays in certain punishments.Drawing on an extraordinarily rich variety of philosophical, psychological, and historical references--from Aristotle and Freud to Nazi ideas about purity--and on legal examples as diverse as the trials of Oscar Wilde and the Martha Stewart insider trading case, this is a major work of legal and moral philosophy. (shrink)

From 1687, the year when Newton published his Principia, to the Crystal Palace Exhibition of 1851, science gradually became central to Western thought and economic development. The book examines how, despite powerful opposition on the Continent, a Newtonian understanding gained acceptance and practical application.

In lieu of an abstract, here is a brief excerpt of the content:70 HUME'S LETTER TO STEWART A Note on a Paper by D. C. Stove In a recent paper, D. C. Stove raises an historical problem. There exists a letter, written in 1754 by Hume to John Stewart, then Professor of Natural Philosophy at Edinburgh, in which the following words occur:. „. J never asserted so absurd a Proposition, as that any thing might arise without a Cause: (...) I only maintained, that our Certainty of the Falsehood of that Proposition proceeded neither from Intuition nor Demonstration; but from another Source. Some commentators, most notably Norman Kemp-Smith, take this as telling strongly in favour of a non-sceptical reading of Hume. Stove undertakes to show beyond reasonable doubt that the claim made in the letter is in blatant contradiction with central theses of Hume's published philosophy, so that it has to be regarded as useless as evidence for the interpretation of the latter. There is a mystery as to how Hume came to say something so clearly false about what he himself had written; Stove offers certain conjectures, none of which he finds wholly satisfactory. As the conclusion of the first, exegetical, part of his article, Stove advances the thesis that Hume held the falsity of the Causal Principle to be possible in at least three senses of "possible". These senses he specifies accurately, but doesn't wish to rest anything on the detail of his specification of the third; it is important only that it be stronger than either of the preceding two. This done, he takes a look at the letter to Stewart, and says, with reference to the first part of the 71 passage quoted above: That something might begin to exist without a cause, is evidently equivalent to the proposition that it is possib Ie for something to begin to exist without a cause. That, in turn, is evidently equivalent to the proposition that the falsity of the Causal Principle is possible. (Stove's o underlining). It follows that what Hume says in the letter is simply false. It could be true only if the "might" referred to some sense of possibility even weaker than the weakest of Stove's three senses. But since that is mere self-consistency, there is no such sense. Now the argument to the contradiction relies on reading "might" as "it is possible", in some sense of those words. Stove says, as we have seen, that they are "evidently equivalent", but the equivalence is certainly not evident, and it may well be asked whether it exists at all. After all, there are English constructions with "might" which don't have modal force: "Do you think something might have happened to them without our knowing about it?" The hearer is not, of course, being asked whether it- is possible that something should have happened without their knowledge; he is being asked for his opinion on whether something actually has so happened. "Most unlikely", would be a perfectly natural and acceptable response. Again : "ïou stay here, to take care of any problem that might arise before we get back". Obviously it is not intended that the hearer should start taking precautions against all possibilities, only that he should cope with whatever actually arises, if anything. 72 This is quite normal modern usage, and I know no reason to think that it wasn't also norT.il usage in the 18th Century. Admittedly, it isn't modern philocophers ' usage - we would be very careful, in writing or; logical matters, not to use the word "might" unless it was definitely the modal proposition that we had in mind, but earlier times haven't always been so professional about their vocabulary. Certainly, if Hume, in the letter to Stewart, was denying that he had ever asserted the possibility of the falsehood of the Causal Principle it would be, as Stove shows, extremely hard to see what he could have been thinking of. But if what he meant could have been as well expressed by "I never asserted... that anything arises without a cause" then most of Stove's problems are over, for there is no 3 conflict with any of the theses (1) - (3) which he... (shrink)

The publish-or-perish paradigm is a prevailing facet of science. We apply game theory to show that, under rather weak assumptions, this publication scenario takes the form of a prisoner’s dilemma, which constitutes a substantial obstacle to beneficial delayed publication of more complete results. One way of avoiding this obstacle while allowing researchers to establish priority of discoveries would be an updated “pli cacheté”, a sealed envelope concept from the 1700s. We describe institutional rules that could additionally favour high-quality work and (...) publications and provide examples of such policies that are already in place. Our analysis should be extended to other publication scenarios and the role of other stakeholders such as scientific journals or sponsors. (shrink)

The authors present a case study involving truth telling responsibilities in the setting of nonepileptic seizures. Specifically, over the course of several suspected nonepileptic seizures, a patient’s seizures stopped after he received a saline flush meant to precede the administration of anti-seizure medication. The patient and his surrogate believed he had received the medication each time, and the team wondered whether they should disclose the truth. Some worried that disclosure would reinforce the suspected psychogenic behavior, exacerbating the patient’s condition. In (...) this way, the case study presents a twist on the traditional truth telling archetype. While most truth telling cases center on navigating cultural differences or worries about emotional harm, this case presented concerns about medical harm in the form of exacerbating the patient’s condition. The authors describe the complex patient-family-team dynamic that preceded this ethical dilemma, describe the case, analyze the ethical issue, and describe the outcome. (shrink)

It is now generally agreed that in Aristotle's Poetics, ch. 13 means ‘mistake of fact’. The moralizing interpretation favoured by our Victorian forebears and their continental counterparts was one of the many misunderstandings fostered by their moralistic society, and in our own enlightened erais revealed as an aberration. In challenging this orthodoxy I am not moved by any particular enthusiasm for Victoriana, nor do I want to revive the view that means simply ‘moral flaw’ or ‘morally wrong action’. I shall (...) try to show that the word has a range of applications, from ‘ignorance of fact’ at one end to ‘moral defect’, ‘moral error’, at the other, and that the modern orthodoxy, though not as clearly wrong as the moralizing interpretation it displaced, restricts Aristotle's meaning in a way he did not intend, and does lessthan justice to his analysis of classical drama. (shrink)

It has long been accepted as a principle by editors and writers on Greek metre that brevis in longo and hiatus in tragic lyrics often coincide with some kind of sense-pause. The object of this inquiry is to determine the incidence of pause in such places, and show that it is significantly high; to show that there is a comparable incidence in the corresponding places in strophic systems; to show that period-ends determined by criteria other than brevis and hiatus are (...) attended by similar conditions. It might seem that if all this were true it would have been recognized long ago, particularly as the connection between sense and metrical structure, and symmetry of sense in strophe and antistrophe, has often been pointed out. (shrink)

So Pearson. The strange series of hypodochmiacs here and atO.T.1207 ff., with brevis in longo without pause atAj.421 andO.T.1208, seems metrically self-contained, despite their syntactical interdependence (esp.Aj.421–2οὐκέτ' ἄνδρα μὴ | τόνδ' ἴδητ', so that the word-overlap ofοἷονinto iambics in Pearson's text is unlikely.ἑξερῶ μέγαshould therefore be writtenplena scriptura. Thenοἷον οὔτιν' ἁ Τροί|α στρατοῦ…is possible, but the ithyphallic with word-overlap, sometimes found in the syncopated iambics of Aeschylus, is foreign to Sophocles. Divideἐξερῶ μέγα, | οἷον οὔτινα | Τροία…Thenϕίλοι τοῖσδ' ὁμοῦ = (...) οἷον οὔτινα, i.e.δ= hyp., which is not certainly found, and the antistrophe has two syllables extra. (shrink)

In her masterly article on this passge, Dr. Christiane Sourvinou-Inwood goes most of the way towards solving two serious problems: the text of Lys. 645, where the vulgate makes the ‘bears’ more than ten years old, contrary to all other evidence; and the meaning of of A. Ag. 239 . She argues cogently that in Aeschylus means ‘shedding’ the saffron robe, as most editors including Fraenkel have thought, and not ‘letting her robes fall to the ground’ as Lloyd-Jones, followed by (...) Page, has argued. (shrink)